- To stop from lack of power. 2. To tire out or cause to decline in health. 3. To collide with and knock over. 4. To chase and capture. 5. To trace the source of something. 6. To disparage someone. 7. To look over or review. 8. In baseball, to tag out a base runner.
Examples:
- Don't run him down, he's a talented actor.
Origin: Mid-1700s for sense 1